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MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata

BACKGROUND: We found microRNA (miR)-1246 to be significantly differentially expressed between severe active alopecia areata (AA) patients and healthy individuals. OBJECTIVE: To explore the role and mechanism of miR-1246 in severe AA. METHODS: Expression of miR-1246, dual-specific tyrosine phosphoryl...

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Detalles Bibliográficos
Autores principales: Qi, Si-si, Miao, Ying, Sheng, You-yu, Hu, Rui-ming, Zhao, Jun, Yang, Qin-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905862/
https://www.ncbi.nlm.nih.gov/pubmed/36750458
http://dx.doi.org/10.5021/ad.22.126