Cargando…
Impact of phylogeny on structural contact inference from protein sequence data
Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins. They rely on correlations in amino acid usage at contacting sites. Because homologous proteins share a common ancestry, their sequences also feature phylogene...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905998/ https://www.ncbi.nlm.nih.gov/pubmed/36751926 http://dx.doi.org/10.1098/rsif.2022.0707 |