Distinct transcriptional signatures in purified circulating immune cells drive heterogeneity in disease location in IBD

OBJECTIVE: To infer potential mechanisms driving disease subtypes among patients with inflammatory bowel disease (IBD), we profiled the transcriptome of purified circulating monocytes and CD4 T-cells. DESIGN: RNA extracted from purified monocytes and CD4 T-cells derived from the peripheral blood of...

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Detalles Bibliográficos
Autores principales: Verstockt, Bram, Verstockt, Sare, Cremer, Jonathan, Sabino, João, Ferrante, Marc, Vermeire, Severine, Sudhakar, Padhmanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906185/
https://www.ncbi.nlm.nih.gov/pubmed/36746519
http://dx.doi.org/10.1136/bmjgast-2022-001003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906185/
https://www.ncbi.nlm.nih.gov/pubmed/36746519
http://dx.doi.org/10.1136/bmjgast-2022-001003

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