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The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1

BACKGROUND: Keloid is a dermal fibrotic disease characterized by excessive proliferation of dermal fibroblasts and deposition of excessive collagen. N6-methyladenosine (m6A) plays a significant role in numerous physiological and pathological regulatory processes in the human body. Fat mass and obesi...

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Detalles Bibliográficos
Autores principales: Ren, Shuai, Ji, Yingchang, Wang, Mengmeng, Ye, Maodong, Huang, Lvdong, Cai, Xiangna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906204/
https://www.ncbi.nlm.nih.gov/pubmed/36760238
http://dx.doi.org/10.21037/atm-22-6021