Cargando…
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1
BACKGROUND: Keloid is a dermal fibrotic disease characterized by excessive proliferation of dermal fibroblasts and deposition of excessive collagen. N6-methyladenosine (m6A) plays a significant role in numerous physiological and pathological regulatory processes in the human body. Fat mass and obesi...
Autores principales: | Ren, Shuai, Ji, Yingchang, Wang, Mengmeng, Ye, Maodong, Huang, Lvdong, Cai, Xiangna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906204/ https://www.ncbi.nlm.nih.gov/pubmed/36760238 http://dx.doi.org/10.21037/atm-22-6021 |
Ejemplares similares
-
Substrates of the m(6)A demethylase FTO: FTO-LINE1 RNA axis regulates chromatin state in mESCs
por: Sommerkamp, Pia
Publicado: (2022) -
Targeting the RNA demethylase FTO for cancer therapy
por: Zhou, Lin-Lin, et al.
Publicado: (2021) -
m6A demethylase FTO and osteoporosis: potential therapeutic interventions
por: Huang, Mei, et al.
Publicado: (2023) -
m(6)A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte
por: Li, Kan, et al.
Publicado: (2022) -
Omeprazole improves chemosensitivity of gastric cancer cells by m(6)A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation
por: Feng, Shuitu, et al.
Publicado: (2021)