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Recombinant human angiotensin-converting enzyme 2 plays a protective role in mice with sepsis-induced cardiac dysfunction through multiple signaling pathways dependent on converting angiotensin II to angiotensin 1–7

BACKGROUND: Sepsis-induced cardiac dysfunction (SICD) is a common complication of sepsis and contributes to mortality and the complexity of management in patients with sepsis. Recombinant human angiotensin-converting enzyme 2 (rhACE2) has been reported to protect the heart from injury and dysfunctio...

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Detalles Bibliográficos
Autores principales: Wu, Chunxue, Chen, Yuhong, Zhou, Pan, Hu, Zhenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906207/
https://www.ncbi.nlm.nih.gov/pubmed/36760245
http://dx.doi.org/10.21037/atm-22-6016