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Efficacy and safety of pharmacological interventions for managing sickle cell disease in children and adolescents: protocol for a systematic review with network meta-analysis

INTRODUCTION: Sickle cell disease (SCD), an inherited haemoglobinopathy, has important impact on morbidity and mortality, especially in paediatrics. Previous systematic reviews are limited to adult patients or focused only on few therapies. We aim to synthesise the evidence on efficacy and safety of...

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Detalles Bibliográficos
Autores principales: Tonin, Fernanda S, Ginete, Catarina, Fernandez-Llimos, Fernando, Ferreira, Joana, Delgadinho, Mariana, Brito, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906260/
https://www.ncbi.nlm.nih.gov/pubmed/36746535
http://dx.doi.org/10.1136/bmjopen-2022-064872