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Efficacy and safety of pharmacological interventions for managing sickle cell disease in children and adolescents: protocol for a systematic review with network meta-analysis
INTRODUCTION: Sickle cell disease (SCD), an inherited haemoglobinopathy, has important impact on morbidity and mortality, especially in paediatrics. Previous systematic reviews are limited to adult patients or focused only on few therapies. We aim to synthesise the evidence on efficacy and safety of...
Autores principales: | Tonin, Fernanda S, Ginete, Catarina, Fernandez-Llimos, Fernando, Ferreira, Joana, Delgadinho, Mariana, Brito, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906260/ https://www.ncbi.nlm.nih.gov/pubmed/36746535 http://dx.doi.org/10.1136/bmjopen-2022-064872 |
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