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Current understanding of metal-dependent amyloid-β aggregation and toxicity

The discovery of effective therapeutics targeting amyloid-β (Aβ) aggregates for Alzheimer's disease (AD) has been very challenging, which suggests its complicated etiology associated with multiple pathogenic elements. In AD-affected brains, highly concentrated metals, such as copper and zinc, a...

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Detalles Bibliográficos
Autores principales: Yi, Yelim, Lim, Mi Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906324/
https://www.ncbi.nlm.nih.gov/pubmed/36794021
http://dx.doi.org/10.1039/d2cb00208f