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Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury

Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of motor circuits during which supraspinal connections form new contacts onto spinal relay neurons. We have recently identified a critical role of the presynaptic organizer FGF22 for the formation of new synaps...

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Detalles Bibliográficos
Autores principales: Aljović, Almir, Jacobi, Anne, Marcantoni, Maite, Kagerer, Fritz, Loy, Kristina, Kendirli, Arek, Bräutigam, Jonas, Fabbio, Luca, Van Steenbergen, Valérie, Pleśniar, Katarzyna, Kerschensteiner, Martin, Bareyre, Florence M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906383/
https://www.ncbi.nlm.nih.gov/pubmed/36601738
http://dx.doi.org/10.15252/emmm.202216111