A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function

Group A streptococci have evolved multiple strategies to evade human antibodies, making it challenging to create effective vaccines or antibody treatments. Here, we have generated antibodies derived from the memory B cells of an individual who had successfully cleared a group A streptococcal infecti...

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Detalles Bibliográficos
Autores principales: Bahnan, Wael, Happonen, Lotta, Khakzad, Hamed, Kumra Ahnlide, Vibha, de Neergaard, Therese, Wrighton, Sebastian, André, Oscar, Bratanis, Eleni, Tang, Di, Hellmark, Thomas, Björck, Lars, Shannon, Oonagh, Malmström, Lars, Malmström, Johan, Nordenfelt, Pontus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906385/
https://www.ncbi.nlm.nih.gov/pubmed/36507602
http://dx.doi.org/10.15252/emmm.202216208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906385/
https://www.ncbi.nlm.nih.gov/pubmed/36507602
http://dx.doi.org/10.15252/emmm.202216208

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