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Activated protein C attenuates pulmonary coagulopathy in patients with acute respiratory distress syndrome

OBJECTIVE: Acute respiratory distress syndrome (ARDS) frequently complicates critical illness. We hypothesized that an infusion of recombinant human activated protein C (rh-APC), a natural anticoagulant, would attenuate pulmonary coagulopathy and injury. METHODS: In this sub study of a multicenter o...

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Detalles Bibliográficos
Autores principales: Cornet, A.D., Hofstra, J.J., Vlaar, A.P., Tuinman, P.R., Levi, M., Girbes, A.R., Schultz, M.J., Groeneveld, A.B., Beishuizen, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906436/
https://www.ncbi.nlm.nih.gov/pubmed/23433188
http://dx.doi.org/10.1111/jth.12179