Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load

Troubling disparities in COVID-19–associated mortality emerged early, with nearly 70% of deaths confined to Black/African American (AA) patients in some areas. However, targeted studies on this vulnerable population are scarce. Here, we applied multiomics single-cell analyses of immune profiles from...

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Detalles Bibliográficos
Autores principales: Eddins, Devon J., Yang, Junkai, Kosters, Astrid, Giacalone, Vincent D., Pechuan-Jorge, Ximo, Chandler, Joshua D., Eum, Jinyoung, Babcock, Benjamin R., Dobosh, Brian S., Hernández, Mindy R., Abdulkhader, Fathma, Collins, Genoah L., Orlova, Darya Y., Ramonell, Richard P., Sanz, Ignacio, Moussion, Christine, Eun-Hyung Lee, F., Tirouvanziam, Rabindra M., Ghosn, Eliver E. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906672/
https://www.ncbi.nlm.nih.gov/pubmed/36399523
http://dx.doi.org/10.1182/bloodadvances.2022008834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906672/
https://www.ncbi.nlm.nih.gov/pubmed/36399523
http://dx.doi.org/10.1182/bloodadvances.2022008834

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