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Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs

[Image: see text] Membrane transporters are the key determinants of the homeostasis of endogenous compounds in the cells and their exposure to drugs. However, the substrate specificities of distinct transporters can overlap. In the present study, the interactions of l-type amino acid transporter 1 (...

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Detalles Bibliográficos
Autores principales: Huttunen, Johanna, Kronenberger, Thales, Montaser, Ahmed B., Králová, Adéla, Terasaki, Tetsuya, Poso, Antti, Huttunen, Kristiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906736/
https://www.ncbi.nlm.nih.gov/pubmed/36688491
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00948