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Tumor Targeting of (211)At-Labeled Antibody under Sodium Ascorbate Protection against Radiolysis
[Image: see text] Astatine-211 ((211)At) is an alpha emitter applicable to radioimmunotherapy (RIT), a cancer treatment that utilizes radioactive antibodies to target tumors. In the preparation of (211)At-labeled monoclonal antibodies ((211)At-mAbs), the possibility of radionuclide-induced antibody...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906747/ https://www.ncbi.nlm.nih.gov/pubmed/36573995 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00869 |