Tumor Targeting of (211)At-Labeled Antibody under Sodium Ascorbate Protection against Radiolysis

[Image: see text] Astatine-211 ((211)At) is an alpha emitter applicable to radioimmunotherapy (RIT), a cancer treatment that utilizes radioactive antibodies to target tumors. In the preparation of (211)At-labeled monoclonal antibodies ((211)At-mAbs), the possibility of radionuclide-induced antibody...

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Detalles Bibliográficos
Autores principales: Takashima, Hiroki, Ohnuki, Kazunobu, Manabe, Shino, Koga, Yoshikatsu, Tsumura, Ryo, Anzai, Takahiro, Wang, Yang, Yin, Xiaojie, Sato, Nozomi, Shigekawa, Yudai, Nambu, Akihiro, Usuda, Sachiko, Haba, Hiromitsu, Fujii, Hirofumi, Yasunaga, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906747/
https://www.ncbi.nlm.nih.gov/pubmed/36573995
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00869

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