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Effect of Cisplatin and Its Cationic Analogues in the Phase Behavior and Permeability of Model Lipid Bilayers

[Image: see text] Increasing evidence suggests a critical role of lipids in both the mechanisms of toxicity and resistance of cells to platinum(II) complexes. In particular, cisplatin and other analogues were reported to interact with lipids and transiently promote lipid phase changes both in the bu...

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Detalles Bibliográficos
Autores principales: Martinho, Nuno, Marquês, Joaquim M. T., Todoriko, Iryna, Prieto, Manuel, de Almeida, Rodrigo F.M., Silva, Liana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906771/
https://www.ncbi.nlm.nih.gov/pubmed/36700695
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00321