Embedding Dynamics in Intrinsic Physicochemical Profiles of Market-Stage Antibody-Based Biotherapeutics

[Image: see text] Adequate stability, manufacturability, and safety are crucial to bringing an antibody-based biotherapeutic to the market. Following the concept of holistic in silico developability, we introduce a physicochemical description of 91 market-stage antibody-based biotherapeutics based o...

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Detalles Bibliográficos
Autores principales: Licari, Giuseppe, Martin, Kyle P., Crames, Maureen, Mozdzierz, Joseph, Marlow, Michael S., Karow-Zwick, Anne R., Kumar, Sandeep, Bauer, Joschka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906779/
https://www.ncbi.nlm.nih.gov/pubmed/36573887
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906779/
https://www.ncbi.nlm.nih.gov/pubmed/36573887
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00838

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