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A novel intergenic region (chr2: 30,193,816)-ALK fusion shows sensitivity to Alectinib in lung adenocarcinoma

BACKGROUND: Anaplastic lymphoma kinase (ALK) rearrangement, which is mostly showed as fused with echinoderm microtubule-associated protein-like 4 gene (EML4), accounts 3–7% of all common mutations in non-small lung cancer (NSCLC). An intergenic region (chr2: 30,193,816), which located on upstream of...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Du, Ge, Niu, Man, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906856/
https://www.ncbi.nlm.nih.gov/pubmed/36755262
http://dx.doi.org/10.1186/s12890-023-02351-5