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Melanophages give rise to hyperreflective foci in AMD, a disease-progression marker

Retinal melanosome/melanolipofuscin-containing cells (MCCs), clinically visible as hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of age-related macular degeneration (AMD), are widely believed to be migrating retinal pigment epithelial (RPE) cells. Using hum...

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Detalles Bibliográficos
Autores principales: Augustin, Sebastien, Lam, Marion, Lavalette, Sophie, Verschueren, Anna, Blond, Frédéric, Forster, Valérie, Przegralek, Lauriane, He, Zhiguo, Lewandowski, Daniel, Bemelmans, Alexis-Pierre, Picaud, Serge, Sahel, José-Alain, Mathis, Thibaud, Paques, Michel, Thuret, Gilles, Guillonneau, Xavier, Delarasse, Cécile, Sennlaub, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906876/
https://www.ncbi.nlm.nih.gov/pubmed/36755326
http://dx.doi.org/10.1186/s12974-023-02699-9