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Tofacitinib as a maintenance therapy in patients with ulcerative colitis stratified by OCTAVE Sustain baseline Mayo endoscopic subscore

BACKGROUND: Tofacitinib is an oral small molecule Janus kinase inhibitor for the treatment of ulcerative colitis. We evaluated tofacitinib efficacy and safety in the 52-week maintenance study, OCTAVE Sustain, by baseline Mayo endoscopic subscore (MES) following 8-week induction. METHODS: The proport...

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Detalles Bibliográficos
Autores principales: Lee, Scott D., Allegretti, Jessica R., Steinwurz, Flavio, Connelly, Susan B., Lawendy, Nervin, Paulissen, Jerome, Gecse, Krisztina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906955/
https://www.ncbi.nlm.nih.gov/pubmed/36755231
http://dx.doi.org/10.1186/s12876-022-02508-2