Cargando…

Synthesis and characterisation of new antimalarial fluorinated triazolopyrazine compounds

Nine new fluorinated analogues were synthesised by late-stage functionalisation using Diversinate™ chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4). The structures of all analogues were fully characterised by NMR, UV and MS data analysis; three triazolopyrazines were c...

Descripción completa

Detalles Bibliográficos
Autores principales: Lum, Kah Yean, White, Jonathan M, Johnson, Daniel J G, Avery, Vicky M, Davis, Rohan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907012/
https://www.ncbi.nlm.nih.gov/pubmed/36761470
http://dx.doi.org/10.3762/bjoc.19.11