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Asthmatic lung fibroblasts promote type 2 immune responses via endoplasmic reticulum stress response dependent thymic stromal lymphopoietin secretion

Lung fibroblasts contribute to asthma pathology partly through modulation of the immune environment in the airway. Tumor necrosis factor-α (TNFα) expression is upregulated in asthmatic lungs. How asthmatic lung fibroblasts respond to TNFα stimulation and subsequently regulate immune responses is not...

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Detalles Bibliográficos
Autores principales: Drake, Li Y., Koloko Ngassie, Maunick Lefin, Roos, Benjamin B., Teske, Jacob J., Prakash, Y. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907026/
https://www.ncbi.nlm.nih.gov/pubmed/36760534
http://dx.doi.org/10.3389/fphys.2023.1064822