CONTRABASS: exploiting flux constraints in genome-scale models for the detection of vulnerabilities

MOTIVATION: Despite the fact that antimicrobial resistance is an increasing health concern, the pace of production of new drugs is slow due to the high cost and uncertain success of the process. The development of high-throughput technologies has allowed the integration of biological data into detai...

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Detalles Bibliográficos
Autores principales: Oarga, Alexandru, Bannerman, Bridget P, Júlvez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907045/
https://www.ncbi.nlm.nih.gov/pubmed/36692133
http://dx.doi.org/10.1093/bioinformatics/btad053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907045/
https://www.ncbi.nlm.nih.gov/pubmed/36692133
http://dx.doi.org/10.1093/bioinformatics/btad053

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