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SLGNN: synthetic lethality prediction in human cancers based on factor-aware knowledge graph neural network

MOTIVATION: Synthetic lethality (SL) is a form of genetic interaction that can selectively kill cancer cells without damaging normal cells. Exploiting this mechanism is gaining popularity in the field of targeted cancer therapy and anticancer drug development. Due to the limitations of identifying S...

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Detalles Bibliográficos
Autores principales:	Zhu, Yan, Zhou, Yuhuan, Liu, Yang, Wang, Xuan, Li, Junyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907046/ https://www.ncbi.nlm.nih.gov/pubmed/36645245 http://dx.doi.org/10.1093/bioinformatics/btad015

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