Novel sialoglycan linkage for constructing adjuvant-protein conjugate as potent vaccine for COVID-19

Self-adjuvanting protein vaccines have been proved to be highly immunogenic with efficient codelivery of adjuvant and antigen. Current protein vaccines with built-in adjuvants are all modified at the peptide backbone of antigen protein, which could not achieve minor epitope interference and adjuvant...

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Detalles Bibliográficos
Autores principales: Wen, Yu, Zhang, Ru-Yan, Wang, Jian, Zhou, Shi-Hao, Peng, Xiao-Qian, Ding, Dong, Zhang, Zhi-Ming, Wei, Hua-Wei, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907060/
https://www.ncbi.nlm.nih.gov/pubmed/36716860
http://dx.doi.org/10.1016/j.jconrel.2023.01.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907060/
https://www.ncbi.nlm.nih.gov/pubmed/36716860
http://dx.doi.org/10.1016/j.jconrel.2023.01.062

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