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Novel sialoglycan linkage for constructing adjuvant-protein conjugate as potent vaccine for COVID-19
Self-adjuvanting protein vaccines have been proved to be highly immunogenic with efficient codelivery of adjuvant and antigen. Current protein vaccines with built-in adjuvants are all modified at the peptide backbone of antigen protein, which could not achieve minor epitope interference and adjuvant...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907060/ https://www.ncbi.nlm.nih.gov/pubmed/36716860 http://dx.doi.org/10.1016/j.jconrel.2023.01.062 |