Muscle injury causes long-term changes in stem-cell DNA methylation

Injury to muscle brings about the activation of stem cells, which then generate new myocytes to replace damaged tissue. We demonstrate that this activation is accompanied by a dramatic change in the stem-cell methylation pattern that prepares them epigenetically for terminal myocyte differentiation....

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Detalles Bibliográficos
Autores principales: Falick Michaeli, Tal, Sabag, Ofra, Fok, Rimma, Azria, Batia, Monin, Jonathan, Nevo, Yuval, Gielchinsky, Yuval, Berman, Benjamin P., Cedar, Howard, Bergman, Yehudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907067/
https://www.ncbi.nlm.nih.gov/pubmed/36534800
http://dx.doi.org/10.1073/pnas.2212306119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907067/
https://www.ncbi.nlm.nih.gov/pubmed/36534800
http://dx.doi.org/10.1073/pnas.2212306119

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