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A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin
The design of selective metal-binding sites is a challenge in both small-molecule and macromolecular chemistry. Selective recognition of manganese (II)—the first-row transition metal ion that tends to bind with the lowest affinity to ligands, as described by the Irving-Williams series—is particularl...
Autores principales: | Park, Jennifer, Cleary, Michael B., Li, Danyang, Mattocks, Joseph A., Xu, Jiansong, Wang, Huan, Mukhopadhyay, Somshuvra, Gale, Eric M., Cotruvo, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907080/ https://www.ncbi.nlm.nih.gov/pubmed/36508659 http://dx.doi.org/10.1073/pnas.2212723119 |
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