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Central tolerance promoted by cell chimerism

Historically, successful allotransplantation was only achieved by utilizing powerful immunosuppressive drugs that were exposing the patient to severe opportunistic infections. The thymus of the transplant recipient renders such therapy obligatory as it constitutively blocks self-reactive T cells whi...

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Detalles Bibliográficos
Autores principales: Zeleniak, Ann, Trucco, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907097/
https://www.ncbi.nlm.nih.gov/pubmed/36534805
http://dx.doi.org/10.1073/pnas.2214989119