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Central tolerance promoted by cell chimerism
Historically, successful allotransplantation was only achieved by utilizing powerful immunosuppressive drugs that were exposing the patient to severe opportunistic infections. The thymus of the transplant recipient renders such therapy obligatory as it constitutively blocks self-reactive T cells whi...
Autores principales: | Zeleniak, Ann, Trucco, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907097/ https://www.ncbi.nlm.nih.gov/pubmed/36534805 http://dx.doi.org/10.1073/pnas.2214989119 |
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