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Creative destruction: New protein folds from old

Mechanisms of emergence and divergence of protein folds pose central questions in biological sciences. Incremental mutation and stepwise adaptation explain relationships between topologically similar protein folds. However, the universe of folds is diverse and riotous, suggesting more potent and cre...

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Detalles Bibliográficos
Autores principales: Alvarez-Carreño, Claudia, Gupta, Rohan J., Petrov, Anton S., Williams, Loren Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907106/
https://www.ncbi.nlm.nih.gov/pubmed/36534803
http://dx.doi.org/10.1073/pnas.2207897119