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Manganese-dependent microRNA trimming by 3′→5′ exonucleases generates 14-nucleotide or shorter tiny RNAs

MicroRNAs (miRNAs) are about 22-nucleotide (nt) noncoding RNAs forming the effector complexes with Argonaute (AGO) proteins to repress gene expression. Although tiny RNAs (tyRNAs) shorter than 19 nt have been found to bind to plant and vertebrate AGOs, their biogenesis remains a long-standing questi...

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Detalles Bibliográficos
Autores principales: Sim, GeunYoung, Kehling, Audrey C., Park, Mi Seul, Secor, Jackson, Divoky, Cameron, Zhang, Huaqun, Malhotra, Nipun, Bhagdikar, Divyaa, Abd El-Wahab, Ekram W., Nakanishi, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907110/
https://www.ncbi.nlm.nih.gov/pubmed/36508664
http://dx.doi.org/10.1073/pnas.2214335119