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PLK1-ELAVL1/HuR-miR-122 signaling facilitates hepatitis C virus proliferation

The liver-specific microRNA, miR-122, plays an essential role in the propagation of hepatitis C virus (HCV) by binding directly to the 5′-end of its genomic RNA. Despite its significance for HCV proliferation, the host factors responsible for regulating miR-122 remain largely unknown. In this study,...

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Detalles Bibliográficos
Autores principales: Seo, Yoona, Kang, Yura, Ham, Youngwook, Kim, Mi-Hwa, Kim, Seong-Jun, Yoon, Seung Kew, Jang, Sung Key, Park, Jong Bae, Cho, Sungchan, Kim, Jong Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907111/
https://www.ncbi.nlm.nih.gov/pubmed/36512502
http://dx.doi.org/10.1073/pnas.2214911119