De novo mapping of α-helix recognition sites on protein surfaces using unbiased libraries

The α-helix is one of the most common protein surface recognition motifs found in nature, and its unique amide-cloaking properties also enable α-helical polypeptide motifs to exist in membranes. Together, these properties have inspired the development of α-helically constrained (Helicon) therapeutic...

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Detalles Bibliográficos
Autores principales: Li, Kunhua, Tokareva, Olena S., Thomson, Ty M., Wahl, Sebastian C. T., Travaline, Tara L., Ramirez, Jessica D., Choudary, Santosh K., Agarwal, Sorabh, Walkup, Ward G., Olsen, Tivoli J., Brennan, Matthew J., Verdine, Gregory L., McGee, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907135/
https://www.ncbi.nlm.nih.gov/pubmed/36534810
http://dx.doi.org/10.1073/pnas.2210435119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907135/
https://www.ncbi.nlm.nih.gov/pubmed/36534810
http://dx.doi.org/10.1073/pnas.2210435119

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