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Quality assessment and refinement of chromatin accessibility data using a sequence-based predictive model

Chromatin accessibility assays are central to the genome-wide identification of gene regulatory elements associated with transcriptional regulation. However, the data have highly variable quality arising from several biological and technical factors. To surmount this problem, we developed a sequence...

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Detalles Bibliográficos
Autores principales: Han, Seong Kyu, Muto, Yoshiharu, Wilson, Parker C., Humphreys, Benjamin D., Sampson, Matthew G., Chakravarti, Aravinda, Lee, Dongwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907136/
https://www.ncbi.nlm.nih.gov/pubmed/36508674
http://dx.doi.org/10.1073/pnas.2212810119