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Quality assessment and refinement of chromatin accessibility data using a sequence-based predictive model
Chromatin accessibility assays are central to the genome-wide identification of gene regulatory elements associated with transcriptional regulation. However, the data have highly variable quality arising from several biological and technical factors. To surmount this problem, we developed a sequence...
Autores principales: | Han, Seong Kyu, Muto, Yoshiharu, Wilson, Parker C., Humphreys, Benjamin D., Sampson, Matthew G., Chakravarti, Aravinda, Lee, Dongwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907136/ https://www.ncbi.nlm.nih.gov/pubmed/36508674 http://dx.doi.org/10.1073/pnas.2212810119 |
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