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A single vaccination of nucleoside-modified Rabies mRNA vaccine induces prolonged highly protective immune responses in mice

BACKGROUND: Rabies is a lethal zoonotic disease that kills approximately 60,000 people each year. Although inactivated rabies vaccines are available, multiple-dose regimensare recommended for pre-exposure prophylaxis or post-exposure prophylaxis,which cuts down the cost- and time-effectiveness, espe...

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Detalles Bibliográficos
Autores principales: Bai, Shimeng, Yang, Tianhan, Zhu, Cuisong, Feng, Meiqi, Zhang, Li, Zhang, Ziling, Wang, Xiang, Yu, Rui, Pan, Xinghao, Zhao, Chen, Xu, Jianqing, Zhang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907168/
https://www.ncbi.nlm.nih.gov/pubmed/36761167
http://dx.doi.org/10.3389/fimmu.2022.1099991