A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice

Atherosclerosis is a chronic inflammatory disease caused by deposition of oxidative low-density lipoprotein (LDL) in the arterial intima which triggers the innate immune response through myeloid cells such as macrophages. Regulatory T cells (Tregs) play an important role in controlling the progressi...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyun, Li, Qiongzhen, George, Varghese, Spanoudis, Catherine, Gilkes, Crystal, Shrestha, Niraj, Liu, Bai, Kong, Lin, You, Lijing, Echeverri, Christian, Li, Liying, Wang, Zheng, Chaturvedi, Pallavi, Muniz, Gabriela J., Egan, Jack O., Rhode, Peter R., Wong, Hing C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907325/
https://www.ncbi.nlm.nih.gov/pubmed/36761778
http://dx.doi.org/10.3389/fimmu.2023.1114802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907325/
https://www.ncbi.nlm.nih.gov/pubmed/36761778
http://dx.doi.org/10.3389/fimmu.2023.1114802

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