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TERT Gene Fusions Characterize a Subset of Metastatic Leydig Cell Tumors
Metastatic Leydig cell tumors (LCT) are rare, difficult to treat malignancies without known underlying molecular-genetic events. We profiled 27 LCT cases using NGS and immunohistochemistry. Our study identified TERT gene fusions as a main genetic alteration and a potential therapeutic target in LCT....
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907364/ https://www.ncbi.nlm.nih.gov/pubmed/33741265 http://dx.doi.org/10.1016/j.clgc.2021.02.002 |