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A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease

BACKGROUND: Chagas disease (CD) has significant global health impact, but safe, effective treatments remain elusive. The nitroimidazole fexinidazole is a potential treatment. METHODS: This double-blind, randomized, placebo-controlled, dose-finding, proof-of-concept study was conducted in Bolivia. Ad...

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Detalles Bibliográficos
Autores principales: Torrico, Faustino, Gascón, Joaquim, Ortiz, Lourdes, Pinto, Jimy, Rojas, Gimena, Palacios, Alejandro, Barreira, Fabiana, Blum, Bethania, Schijman, Alejandro Gabriel, Vaillant, Michel, Strub-Wourgaft, Nathalie, Pinazo, Maria-Jesus, Bilbe, Graeme, Ribeiro, Isabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907522/
https://www.ncbi.nlm.nih.gov/pubmed/35925555
http://dx.doi.org/10.1093/cid/ciac579