Application of mevalonolactone prevents deterioration of epidermal barrier function by accelerating the lamellar granule lipid transport system

BACKGROUND: Fatty acids increase ATP‐binding cassette ABC transporter A12 (ABCA12) levels via an increase in peroxisome proliferator‐activated receptor β/δ (PPAR β/δ). Promoting lipid transport to lamellar granules has been suggested to improve epidermal barrier function in patients with dry skin. O...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Lu, Nan, Lee, KeeSuh, Ye, Lei, Hasegawa, Chiho, Maeda, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907606/
https://www.ncbi.nlm.nih.gov/pubmed/36148627
http://dx.doi.org/10.1111/srt.13202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907606/
https://www.ncbi.nlm.nih.gov/pubmed/36148627
http://dx.doi.org/10.1111/srt.13202

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