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Application of mevalonolactone prevents deterioration of epidermal barrier function by accelerating the lamellar granule lipid transport system
BACKGROUND: Fatty acids increase ATP‐binding cassette ABC transporter A12 (ABCA12) levels via an increase in peroxisome proliferator‐activated receptor β/δ (PPAR β/δ). Promoting lipid transport to lamellar granules has been suggested to improve epidermal barrier function in patients with dry skin. O...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907606/ https://www.ncbi.nlm.nih.gov/pubmed/36148627 http://dx.doi.org/10.1111/srt.13202 |