The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019, constitutes an emerging human pathogen of zoonotic origin. A critical role in protecting the host against invading pathogens is carried out by interferon-stimulated genes (ISGs), the primary effector...

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Detalles Bibliográficos
Autores principales: Song, Liu, Wang, Dianbing, Abbas, Ghulam, Li, Min, Cui, Mengmeng, Wang, Jufang, Lin, Zhanglin, Zhang, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907797/
https://www.ncbi.nlm.nih.gov/pubmed/36758802
http://dx.doi.org/10.1016/j.jbc.2023.102990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907797/
https://www.ncbi.nlm.nih.gov/pubmed/36758802
http://dx.doi.org/10.1016/j.jbc.2023.102990

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