Cargando…

The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019, constitutes an emerging human pathogen of zoonotic origin. A critical role in protecting the host against invading pathogens is carried out by interferon-stimulated genes (ISGs), the primary effector...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Liu, Wang, Dianbing, Abbas, Ghulam, Li, Min, Cui, Mengmeng, Wang, Jufang, Lin, Zhanglin, Zhang, Xian-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907797/ https://www.ncbi.nlm.nih.gov/pubmed/36758802 http://dx.doi.org/10.1016/j.jbc.2023.102990

Ejemplares similares

SARS-CoV-2 main protease cleaves MAGED2 to antagonize host antiviral defense
por: Ju, Xiaohui, et al.
Publicado: (2023)

Construction of Genetically Encoded Biosensors to Monitor Subcellular Compartment-Specific Glutathione Response to Chemotherapeutic Drugs in Acute Myeloid Leukemia Cells
por: Abbas, Ghulam, et al.
Publicado: (2023)

Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A
por: Huang, Hai-xin, et al.
Publicado: (2023)

A switch-on molecular biosensor for detection of caspase-3 and imaging of apoptosis of cells
por: Gong, Rui, et al.
Publicado: (2021)

Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense
por: Guise, Amanda J., et al.
Publicado: (2013)

Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression
por: Génin, Pierre, et al.
Publicado: (2012)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

Structural basis of mRNA cap recognition by Dcp1–Dcp2
por: Mugridge, Jeffrey S, et al.
Publicado: (2016)

The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1
por: Chang, Chung-Te, et al.
Publicado: (2014)

Comparing the In Vitro Stiffness of Straight-DCP, Wave-DCP, and LCP Bone Plates for Femoral Osteosynthesis
por: Mariolani, José Ricardo Lenzi, et al.
Publicado: (2013)

Des-γ-Carboxyprothrombin (DCP) and NX-DCP Expressions and Their Relationship with Clinicopathological Features in Hepatocellular Carcinoma
por: Sumi, Akiko, et al.
Publicado: (2015)

A histone deacetylase inhibitor enhances rice immunity by derepressing the expression of defense-related genes
por: Xu, Yan, et al.
Publicado: (2022)

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
por: Yao, Ya-Li, et al.
Publicado: (2011)

Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors
por: Whitmore, Melanie A., et al.
Publicado: (2022)

Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity
por: Banik, Debarati, et al.
Publicado: (2012)

The Coxsackievirus B 3C(pro) Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling
por: Mukherjee, Amitava, et al.
Publicado: (2011)

Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers
por: Sanaei, Masumeh, et al.
Publicado: (2019)

Chemical Tools to Image the Activity of PAR-Cleaving Proteases
por: Lee, Irene Y., et al.
Publicado: (2023)

Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition
por: Xiong, Haitao, et al.
Publicado: (2016)

Histone deacetylase 3, not histone deacetylase 2, interacts with the major immediate early locus of human cytomegalovirus
por: Huang, Ying, et al.
Publicado: (2011)

SARS-CoV-2 main protease Nsp5 cleaves and inactivates human tRNA methyltransferase TRMT1
por: Lu, Jia-Li, et al.
Publicado: (2023)

DCP annual registration renewal now open
Publicado: (2021)

The application of histone deacetylases inhibitors in glioblastoma
por: Chen, Rui, et al.
Publicado: (2020)

Chemical Phylogenetics of Histone Deacetylases
por: Bradner, James E., et al.
Publicado: (2010)

Histone deacetylases in viral infections
por: Herbein, Georges, et al.
Publicado: (2010)

Butyrate Histone Deacetylase Inhibitors
por: Steliou, Kosta, et al.
Publicado: (2012)

Histone deacetylase signaling in cardioprotection
por: Lehmann, Lorenz H., et al.
Publicado: (2013)

Histone deacetylase 6 in cancer
por: Li, Ting, et al.
Publicado: (2018)

Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8
por: Yan, Wensheng, et al.
Publicado: (2012)

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors
por: Lapierre, Marion, et al.
Publicado: (2016)

The SARS-CoV-2 main protease M(pro) causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
por: Wenzel, Jan, et al.
Publicado: (2021)

Application of a Schizosaccharomyces pombe Edc1-fused Dcp1–Dcp2 decapping enzyme for transcription start site mapping
por: Paquette, David R., et al.
Publicado: (2018)

The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ
por: Klegeris, Andis, et al.
Publicado: (2012)

Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist
por: Soday, Lior, et al.
Publicado: (2019)

Histone deacetylase enzymes and selective histone deacetylase inhibitors for antitumor effects and enhancement of antitumor immunity in glioblastoma
por: Yelton, Caleb J., et al.
Publicado: (2018)

In vivo human brain expression of histone deacetylases in bipolar disorder
por: Tseng, Chieh-En J., et al.
Publicado: (2020)

Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis
por: Mugridge, Jeffrey S., et al.
Publicado: (2018)

Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases
por: Wang, Yonggang, et al.
Publicado: (2014)

Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
por: Hai, Yang, et al.
Publicado: (2017)

The emerging role of histone deacetylase 1 in allergic diseases
por: Wang, Yongfang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_57aet8f8bshqijdlsr3k9pqmcm