A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy

Neutralizing antibodies (nAbs) are important assets to fight COVID-19, but most existing nAbs lose the activities against Omicron subvariants. Here, we report a human monoclonal antibody (Ab08) isolated from a convalescent patient infected with the prototype strain (Wuhan-Hu-1). Ab08 binds to the re...

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Detalles Bibliográficos
Autores principales: Meng, Lu, Zha, Jialu, Zhou, Bingjie, Cao, Long, Jiang, Congli, Zhu, Yuanfei, Li, Teng, Lu, Lu, Zhang, Junqi, Yang, Heng, Feng, Jian, Gu, Zhifeng, Tang, Hong, Jiang, Lubin, Li, Dianfan, Lavillette, Dimitri, Zhang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907810/
https://www.ncbi.nlm.nih.gov/pubmed/36706160
http://dx.doi.org/10.1371/journal.ppat.1011085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907810/
https://www.ncbi.nlm.nih.gov/pubmed/36706160
http://dx.doi.org/10.1371/journal.ppat.1011085

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