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Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans

Programmed DNA double-strand break (DSB) formation is essential for achieving accurate chromosome segregation during meiosis. DSB repair timing and template choice are tightly regulated. However, little is known about how DSB distribution and the choice of repair pathway are regulated along the leng...

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Detalles Bibliográficos
Autores principales: Lascarez-Lagunas, Laura I., Martinez-Garcia, Marina, Nadarajan, Saravanapriah, Diaz-Pacheco, Brianna N., Berson, Elizaveta, Colaiácovo, Mónica P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907818/
https://www.ncbi.nlm.nih.gov/pubmed/36706157
http://dx.doi.org/10.1371/journal.pgen.1010627