Filamin C is Essential for mammalian myocardial integrity

FLNC, encoding filamin C, is one of the most mutated genes in dilated and hypertrophic cardiomyopathy. However, the precise role of filamin C in mammalian heart remains unclear. In this study, we demonstrated Flnc global (Flnc(gKO)) and cardiomyocyte-specific knockout (Flnc(cKO)) mice died in utero...

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Detalles Bibliográficos
Autores principales: Wu, Tongbin, Xu, Yujun, Zhang, Lunfeng, Liang, Zhengyu, Zhou, Xiaohai, Evans, Sylvia M., Chen, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907827/
https://www.ncbi.nlm.nih.gov/pubmed/36706168
http://dx.doi.org/10.1371/journal.pgen.1010630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907827/
https://www.ncbi.nlm.nih.gov/pubmed/36706168
http://dx.doi.org/10.1371/journal.pgen.1010630

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