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Filamin C is Essential for mammalian myocardial integrity
FLNC, encoding filamin C, is one of the most mutated genes in dilated and hypertrophic cardiomyopathy. However, the precise role of filamin C in mammalian heart remains unclear. In this study, we demonstrated Flnc global (Flnc(gKO)) and cardiomyocyte-specific knockout (Flnc(cKO)) mice died in utero...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907827/ https://www.ncbi.nlm.nih.gov/pubmed/36706168 http://dx.doi.org/10.1371/journal.pgen.1010630 |