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Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence
The Arp2/3 complex is an actin nucleator with well-characterized activities in cell morphogenesis and movement, but its roles in nuclear processes are relatively understudied. We investigated how the Arp2/3 complex affects genomic integrity and cell cycle progression using mouse fibroblasts containi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907832/ https://www.ncbi.nlm.nih.gov/pubmed/36706133 http://dx.doi.org/10.1371/journal.pgen.1010045 |